We study how chromatin, synapses, and neural circuits work together to shape memory, helping uncover the biological foundations of mental health, neurological disease, and what makes us who we are.
Mapping Memory. Protecting What's Human.

Memory allows us to learn, adapt, build relationships, and carry our experiences through life. Yet despite its central role in who we are, we still don’t fully understand how memory is formed, maintained, and lost.
Our research investigates how connections across chromatin, synapses, and neural circuits give rise to memory and how disruptions in these systems contribute to neurological disease. By studying these relationships across multiple scales of the brain, we seek to better understand memory dysfunction and help uncover new paths toward treatment.
Our Research


Our Expertise
We investigate the structure-function relationships that connect chromatin, synapses, and neural circuits, using interdisciplinary approaches to better understand memory and brain function.
- Chromatin
- 3d Genome Folding
- Neurobiology
- Synaptic Plasticity
- Neuroplasticity
- Neuroepigenetics
- Neural Connectomes
- Spatial Technology Development
- Genome Structure-function
- Synapse Structure-function
By connecting discoveries across these areas, we can study memory as an integrated system rather than a collection of isolated parts. This perspective helps reveal how changes at one level of the brain can influence function across the whole.
Proud Partners
Scientific discovery is a collaborative effort. We are grateful for the organizations, institutions, and supporters whose partnership helps make this work possible.
Our People
We believe the best ideas emerge when diverse expertise, curiosity, and collaboration come together around a shared question.
Our lab brings together researchers from neurobiology, genomics, engineering, computation, and technology development to explore memory from multiple perspectives.

Join Us
We’re always looking for curious, collaborative people who want to push the boundaries of neuroscience and memory research. Explore opportunities to contribute, learn, and help shape the future of discovery.
Lab Updates
News, milestones, publications, events, and discoveries from across the Cremins Lab community.
Our Funding

Our work is supported by the New York Stem Cell Foundation,the Alfred P. Sloan Foundation, the National Science Foundation, the NationalInstitute of Mental Health, the National Institute of Neural Disorders andStroke, the National Science Foundation (NSF), NIH Common fund initiatives, theFriedreich’s Ataxia Research Alliance, the Chan Zuckerberg Initiative (CZI),the Cure Huntington’s Disease Initiative (CHDI), and the NIH 4D Nucleome CommonFund Initiative.





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