The Cremins lab aims to understand how chromatin works through long-range physical folding mechanisms to encode neuronal specification and long-term synaptic plasticity in healthy and diseased neural circuits. We pursue a multi-disciplinary approach integrating data across biological scales in the brain, including molecular Chromosome-Conformation-Capture sequencing technologies, single-cell imaging, optogenetics, genome engineering, induced pluripotent stem cell differentiation to neurons/organoids, and in vitro and in vivo electrophysiological measurements.

Emily Pickup joins the lab – welcome Emily!

Harshini Chandrashekar successfully passes her PhD qualifying exam!

Thomas Malachowski successfully passes his PhD qualifying exam!

Rohan Patel joins the lab – welcome Rohan!

Avi Waldman joins the lab – welcome Avi!

Brian Franklin passes his Step One exam. Congratulations Brian!

Zoltan Simandi attends CZI faculty application training program.

Jordan Barnett joins the lab – welcome Jordan!

Dan Emerson successfully passes his PhD qualifying exam!

Linda Zhou, PhD wins the Saul Winegrad award for 2021 best thesis for Penn GCB.

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  Our work is supported by the New York Stem Cell Foundation, the Alfred P. Sloan Foundation, the National Science Foundation, the National Institute of Mental Health, the National Institute of Neural Disorders and Stroke, NIH Common fund initiatives, the Friedreich’s Ataxia Research Alliance, the Chan Zuckerberg Initiative, and the NIH 4D Nucleome Common Fund Initiative.